This is a standard Nuxeo 5.3.2 setup, using the windows installer and without any specific configuration (no other database, no ldap, etc..).
The Flex samples were checkout and built from http://hg.nuxeo.org/addons/nuxeo-platform-flex at branch 5.3 (summary: Upgrade to stable Granite 1.1.0.GA).
Then I have to add "granite-core-1.1.0.GA.jar" and "granite-seam-1.1.0.GA.jar" in the "NuxeoDM-5.3.2\server\default\lib" directory to avoid ClassNotFoundExeption on Granite classes
Then error in console is :
Caused by: java.lang.NoClassDefFoundError: org/jboss/seam/core/Manager
at org.granite.seam.SeamInterceptor.destroySeamContext(SeamInterceptor.java:222)
at org.granite.seam.SeamInterceptor.after(SeamInterceptor.java:106)
at org.granite.messaging.amf.process.AMF3MessageProcessor.process(AMF3MessageProcessor.java:67)
at org.granite.messaging.amf.process.AMF0MessageProcessor.process(AMF0MessageProcessor.java:71)
at org.granite.messaging.webapp.AMFMessageServlet.doPost(AMFMessageServlet.java:59)
at javax.servlet.http.HttpServlet.service(HttpServlet.java:710)
Moving granite JARs into "NuxeoDM-5.3.2\server\default\deploy\nuxeo.ear\lib", solves the issue.